Meeting for John Trinick and Gerald Offer: January 10th 2020, Leeds

Two highly regarded researchers in the ‘muscle’ field, died this year – Professor John Trinick and Professor Gerald Offer.  We are planning a meeting to honour their life and work, and look forward to future developments.

Coiled coils, myosin, titin and striated muscle: A reflection on the contributions of John Trinick and Gerald Offer.

January 10th 2020

University of Leeds

REGISTRATION IS OPEN: go to https://www.rms.org.uk/discover-engage/event-calendar/meeting-for-john-trinick-and-gerald-offer.html

cost £25, Registration will close in mid December.

Description:

John Trinick and Gerald Offer were leading researchers in the field of coiled coils, myosin, titin and skeletal muscle. Both researchers passed away this year, and the main reason for holding the meeting is to celebrate their contributions to the field, with a look back into how the field has developed over the past 50 years, and to look forward to new exciting developments that build on their contributions.  Our invited speakers reflect this diversity of aims, and include many people who have worked with John and Gerald over their careers, reflecting their rich diversity of research. John made many contributions to the development of electron microscopy, using it to visualise titin and myosin. Gerald was an expert in myosin and coiled coils.

ORGANISERS:  Michelle Peckham, Steve Muench and Peter Knight (University of Leeds, UK), and Prof. Howard White (Eastern Virginia Medical School, USA)

09.30 Arrive & Coffee

10.00 Howard White                       What a pleasure it was to have had John and Gerald as colleagues and friends:  The Influence they both had on my career past and present.

10.30 Belinda Bullard                     The legacy of John’s work on titin in Heidelberg

10.50 KW Ranatunga                     Modelling the Crossbridge Cycle of Muscle

11.05 Pauline Bennett                    Locating titin and MyBP-C on the muscle thick filament

11.20 Tea/coffee

11.40 Roger Craig                           Structural studies of myosin molecules and thick filaments: in the footsteps of Gerald and John

12.10 Annalisa Pastore                  From Titin and Beyond

12.25 Dek Woolfson                        Learning my ABCs with Gerald: Alpbach, Beamsand Coils

12.55 Lunch

13.45 Mathias Gautel                      Rulers, Blueprints and Mysteries of the Sarcomere

14.15 Michelle Peckham                Titin, myosin, and sarcomeric diseases

14.30 Rob Cross                              How stiff is your lever?

14.45 Charlie Scarff                        The structural basis of HCM: Linking mutation to disease

15.00 Tea/Coffee

15.30 Peter Knight                          Working with Gerald Offer and John Trinick on myosins, muscle and meat.

16.10                                                  Closing remarks

16.30. Drinks reception

Details to follow

Registration will open on October 1st.  There will be a small registration fee of £25 to cover the costs of catering.

Registration is being handled by the Royal Microscopical Society:

https://www.rms.org.uk/discover-engage/event-calendar/meeting-for-john-trinick-and-gerald-offer.html

Below is a link to the EM movie of myosin 5 'walking' along actin, from Walker et al., 2000, Nature.